Processing ribosomal RNA
نویسندگان
چکیده
منابع مشابه
RNA processing: Pocket guides to ribosomal RNA
The functional role of a recently identified class of small nucleolar (sno) RNAs has been elucidated: the 'box H/ACA' snoRNAs act as guide RNAs, specifying the position of evolutionarily conserved pseudouridines in ribosomal (r)RNA via an rRNA-snoRNA base-pairing interaction that forms a 'pseudouridine pocket'.
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Ribosomal RNA precursors and mature 28S ribosomal RNA from HeLa cells display a highly reproducible secondary structure of hairpin loops after they are spread and examined in an electron microscope. This structure was used to map the linear arrangement of these molecules. Partial digestion with 3'-exonuclease from ascites cell nuclei established that the 28S RNA region is located at the 5'-end ...
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RNase P is a ribonucleoprotein endoribonuclease responsible for the 5' maturation of precursor tRNAs in all organisms. While analyzing mutations in conserved positions of the yeast nuclear RNase P RNA subunit, significant accumulation of an aberrant RNA of approximately 193 nucleotides was observed. This abundant RNA was identified as a 3'extended form of the 5.8S rRNA. This strain also display...
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The synthesis and processing of the 15S and 21S rRNAs have been studied in isolated yeast mitochondria. When mitochondrial transcripts were labeled with [alpha-32p]UTP in an incubation mixture containing 50 microM ATP, the transcripts from the genes for the large and small ribosomal RNAs accumulated in the form of putative precursor molecules. The labeled pre-21S rRNA was converted to mature 21...
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The Bacillus subtilis RNase M5 complex, responsible for the terminal maturation of 5 S rRNA, includes two proteins. One of these proteins is ribosomal protein BL16 (equivalent to Escherichia coli EL18); the other, the alpha component, is required for catalysis. The RNase M5 alpha component has been purified in bulk extensively, and the active polypeptide (Mr approximately 24,000) identified fol...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2002
ISSN: 1465-6906
DOI: 10.1186/gb-spotlight-20020612-02